Diplomatic relations between the Kyrgyz Republic and the United States were established on December 27, 1991. The United States was among the first countries to recognize the independence of Kyrgyzstan.

The Embassy of Kyrgyzstan to the United States was opened in 1992. The same year saw the opening of the U.S. Embassy in Kyrgyzstan, which was one of the first foreign diplomatic missions in the Kyrgyz Republic and Central Asia.

Since Kyrgyzstan’s independence, bilateral relations between Kyrgyzstan and the United States have developed in the spirit of friendship, mutual respect, and desire to promote closer ties in the political, trade and economic, scientific and technological, cultural and humanitarian spheres.

The United States highly values Kyrgyzstan's leadership in promoting democracy, welcoming the commitment of the Kyrgyz Republic in holding free and fair parliamentary elections in 2015 and presidential elections in 2017.

Kyrgyzstan and the United States are making efforts to develop and strengthen cooperation within multilateral platforms such as the UN, OSCE, C5+1, TIFA, WTO and others.